My best advice would be to run seperate wire tracks for all your audio system wiring, keeping power away from RCA & speaker wire.
Turn the volume on your head unit down, and the voloume on your amps up. (use the amps to do the turning while keeping the head unit on pretty standard settings) Make sure the earths for the amps are both do different spots and be sure that they are on bolts connected directly to the car chassie. Be sure not to have much power & earth wire wire exposed from insullation at connections. Make sure all connection are tight and clean. Lastly try to keep the wire from amp to speakers/subs as short as possible, don't leave lengths rolled up under carpet on in you spare wheel hole. (yes i have seen this happen before)
Turn the volume on your head unit down, and the voloume on your amps up. (use the amps to do the turning while keeping the head unit on pretty standard settings) Make sure the earths for the amps are both do different spots and be sure that they are on bolts connected directly to the car chassie. Be sure not to have much power & earth wire wire exposed from insullation at connections. Make sure all connection are tight and clean. Lastly try to keep the wire from amp to speakers/subs as short as possible, don't leave lengths rolled up under carpet on in you spare wheel hole. (yes i have seen this happen before)